DOI: 10.3724/SP.J.1260.2013.30126

Aata Biophysica Sinica (生物物理学报) 2013/29:12 PP.919-924

The Characteristics of Exosomes and Their Roles in Intercellular Communication

Exosomes are small membrane vesicles secreted from various types of cells. Recent studies have shown the abilities of exosomes to incorporate and transfer functional messenger RNA, microRNAs and protein, which suggests that exosomes influence the physiological phenotype of recipient cells. Exosomes have gained much attention for their role in intercellular communication. In this review, the biological function of exosomes and their involvement in physiological and pathological processes were reviewed. Moreover, the potential clinical application of exosomes as biomarkers and therapeutic tools was discussed.

Key words:Exosomes,Intercellular communication,microRNAs,Biomarkers

ReleaseDate:2015-04-19 19:20:50

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