doi:

DOI: 10.3724/SP.J.1008.2010.00904

Academic Journal of Second Military Medical University (第二军医大学学报) 2010/30:8 PP.904-906

Non-elevated cardiovascular risk in patients with primary biliary cirrhosis and hypercholesterolemia


Abstract:
Primary biliary cirrhosis (PBC) is an autoimmune disease with unknown causes. Most PBC patients have abnormal lipid metabolism characterized by hypercholesterolemia. Paradoxically, clinical observations and pre-experimental studies showed that the risk of hyperlipidemia associated cardiovascular event and the mortality of PBC patients were not increased. In this review we summarize the possible reasons and the underlying mechanisms.

Key words:primary biliary cirrhosis,hypercholesterolemia,cardiovascular risk

ReleaseDate:2014-07-21 15:25:19

Funds:National High-tech R&D Program(“863” Program, 2006AA02Z496) and Foundation for Leading Scientists of Science and Technology Commission of Shanghai Municipality (07XD14013).



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