DOI: 10.3724/SP.J.1008.2009.00843

Academic Journal of Second Military Medical University (第二军医大学学报) 2009/29:7 PP.843-845

Bone morphogenetic protein-oriented multi-factor combined application in promoting osteogenesis: recent progress

Bone morphogenetic proteins (BMPs) play a pivotal role in the formation,induction and repair of the bone; BMPs have been confirmed to induce bone formation. Transforming growth factor-beta,insulin-like growth factor-Ⅰ and basic fibroblast growth factor also contribute to bone formation; combination of the factors with BMPs can promote the healing of fracture and non-union,which may have a bright future in orthopedics.

Key words:bone morphogenetic proteins,TGF-β,IGF-Ⅰ,FGF,fractures

ReleaseDate:2014-07-21 14:58:45

Funds:Supported by Specialized Research Fund for Clinical Medicine of Changhai Hospital.

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