doi:

DOI: 10.3724/SP.J.1042.2017.01758

Advances in Psychological Science (心理科学进展) 2017/25:10 PP.1758-1768

Neural mechanisms of pain-related fear and its reduction


Abstract:
Pain-related fear is an important topic in both basic and clinical research of pain. It is associated with pain hypervigilance and followed by avoidance behaviors, thereby resulting in the inaccurate processing of non-pain-related information, the disturbance of the body functions, as well as the exacerbation of pain disability. Individual pain-related fear can influence subjective pain perception and pain-related attention bias and avoidance behavior, as well as plays an important role in the development of chronic pain (e.g., chronic musculoskeletal pain) and the maintenance of physiological dysfunctions. Multiple cortical and sub-cortical brain regions, e.g., amygdala, hippocampus, dorsal anterior cingulate cortex, and prefrontal cortex, involve in the formation and expression of pain-related fear. Existing psychological-behavioral intervention therapies of reducing pain-related fear worked in different stages of pain-related fear formation (consolidation, reconsolidation, and extinction). Nevertheless, due to the complexity of pain-related fear formation and the influences of multiple factors, the effect of current psychological intervention therapies for reducing pain-related fear is not stable, yet there is a great gap between the relevant basic research and clinical applications. Differences of contexts in the formation of pain-related fear, as well as individual personality traits and psychological states, should be well taken into consideration in the future study, which will help reduce or even eliminate the disturbing pain-related fear, thus relieving and removing pain sufferings.

Key words:pain-related fear,reduction of pain-related fear,pain relief,psychological therapies

ReleaseDate:2017-11-17 09:48:04



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