DOI: 10.3724/SP.J.1042.2018.00657

Advances in Psychological Science (心理科学进展) 2018/26:4 PP.657-666

Application of transcranial direct current stimulation in the treatment of attention deficit hyperactivity disorder

Transcranial direct current stimulation (tDCS) treatment of attention deficit hyperactivity disorder (ADHD) is selecting the patient dorsolateral prefrontal cortex (DLPFC) as a stimulating area, by adjusting the cortical excitability, alleviate ADHD symptoms and improve impaired cognitive functions. In view of the problem of tDCS in ADHD treatment, the future from effectiveness, determine the optimal stimulation parameters, individual differences, different subtypes and in combination with other therapies using these five aspects to further study.

Key words:attention deficit hyperactivity disorder,transcranial direct current stimulation,dorsolateral prefrontal cortex

ReleaseDate:2018-05-04 05:07:49

靳彦琴, 姚梅玲, 段桂琴, 王亚哲. (2015). 脑电生物反馈治疗注意缺陷多动障碍患儿疗效分析. 兰州大学学报(医学版), 41(1), 68-70, 74.

李雪姣, 邹枝玲. (2016). 经颅直流电刺激技术在物质依赖治疗中的应用. 心理科学进展, 24(9), 1398-1408.

静进. (2012). 儿童注意缺陷多动障碍诊疗进展. 实用儿科临床杂志, 27(12), 965-970.

王晓静, 汤永隆, 李兵. (2016). 经颅直流电刺激(tDCS)在成瘾中的研究进展. 心理学进展, 6(3), 264-268.

谢娜, 孙龙伟, 徐守军, 曾伟彬. (2016). 儿童注意缺陷多动障碍脑功能及功能连接研究. 磁共振成像, 7(6), 412-416.

张大山, 史慧颖, 刘威, 邱江, 范丰慧. (2015). 经颅直流电刺激在抑郁症治疗中的应用. 心理科学进展, 23(10), 1789-1798.

张晓燕, 杨闯, 梁艳, 林海西, 杜松妹, 王维千, …. 唐闻捷. (2015). 注意缺陷多动障碍亚型间脑fMRI低频振幅差异. 温州医科大学学报, 45(2), 100-105.

朱庆庆, 古桂雄, 花静. (2015). 注意缺陷多动障碍儿童家庭环境危险因素研究. 中国妇幼保健, 30(7), 1074-1077.

Alexander, G. E., DeLong, M. R., & Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annual Review of Neuroscience, 9(1), 357-381.

American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (DSM-5) (5th ed.). Washington DC:American Psychiatric Publishing.

Andrade, A. C., Magnavita, G. M., Allegro, J. V. B. N., Neto, C. E. B. P., de Cássia Saldanha Lucena, R., & Fregni, F. (2014). Feasibility of transcranial direct current stimulation use in children aged 5 to 12 years. Journal of Child Neurology, 29(10), 1360-1365.

Antal, A., Kincses, T. Z., Nitsche, M. A., Bartfai, O., & Paulus, W. (2004). Excitability changes induced in the human primary visual cortex by transcranial direct current stimulation:Direct electrophysiological evidence. Investigative Ophthalmology & Visual Science, 45(2), 702-707.

Bandeira, I. D., Guimarães, R. S. Q., Jagersbacher, J. G., Barretto, T. L., de Jesus-Silva, J. R., Santos, S. N.,... Lucena, R. (2016). Transcranial direct current stimulation in children and Adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD):A pilot study. Journal of Child Neurology, 31(7), 918-924.

Beiser, D. G., Hua, S. E., & Houk, J. C. (1997). Network models of the basal ganglia. Current Opinion in Neurobiology, 7(2), 185-190.

Berger, A., & Posner, M. I. (2000). Pathologies of brain attentional networks. Neuroscience & Biobehavioral Reviews, 24(1), 3-5.

Berryhill, M. E., & Jones, K. T. (2012). tDCS selectively improves working memory in older adults with more education. Neuroscience Letters, 521(2), 148-151.

Booth, J. R., Burman, D. D., Meyer, J. R., Lei, Z., Trommer, B. L., Davenport, N. D.,... Mesulam M. M. (2005). Larger deficits in brain networks for response inhibition than for visual selective attention in attention deficit hyperactivity disorder (ADHD). Journal of Child Psychology and Psychiatry, 46(1), 94-111.

Brunoni, A. R., Valiengo, L., Baccaro, A., Zanão, T. A., de Oliveira, J. F., Goulart, A.,... Fregni, F. (2013). The sertraline vs electrical current therapy for treating depression clinical study:Results from a factorial, randomized, controlled trial. JAMA Psychiatry, 70(4), 383-391.

Cachoeira, C. T., Leffa, D. T., Mittelstadt, S. D., Mendes, L. S. T., Brunoni, A. R., Pinto, J. V.,... Schestatsky, P. (2017). Positive effects of transcranial direct current stimulation in adult patients with attention-deficit/hyperactivity disorder A pilot randomized controlled study. Psychiatry Research, 247, 28-32.

Caye, A., Rocha, T. B.-M., Anselmi, L., Murray, J., Menezes, A. M., Barros, F. C.,... Rohde, L. A. (2016). Attention-deficit/hyperactivity disorder trajectories from childhood to young adulthood:Evidence from a birth cohort supporting a late-onset syndrome. JAMA Psychiatry, 73(7), 705-712.

Clarke, P. J. F., Browning, M., Hammond, G., Notebaert, L., & MacLeod, C. (2014). The causal role of the dorsolateral prefrontal cortex in the modification of attentional bias:Evidence from transcranial direct current stimulation. Biological Psychiatry, 76(12), 946-952.

Cosmo, C., Baptista, A. F., de Araújo, A. N., do Rosário, R. S., Miranda, J. G. V., Montoya, P., & de Sena, E. P. (2015a). A randomized, double-blind, sham-controlled trial of transcranial direct current stimulation in attention-deficit/hyperactivity disorder. PLoS One, 10(8), e0135371.

Cosmo, C., Ferreira, C., Miranda, J. G. V., do Rosário, R. S., Baptista, A. F., Montoya, P., & de Sena, E. P. (2015b). Spreading effect of tDCS in individuals with attention-deficit/hyperactivity disorder as shown by functional cortical networks:A randomized, double-blind, sham-controlled trial. Frontiers in Psychiatry, 6, 111.

Datta, A., Truong, D., Minhas, P., Parra, L. C., & Bikson, M. (2012). Inter-individual variation during transcranial direct current stimulation and normalization of dose using MRI-derived computational models. Frontiers in Psychiatry, 3, 91.

Disner, S. G., Beevers, C. G., Haigh, E. A., & Beck, A. T. (2011). Neural mechanisms of the cognitive model of depression. Nature Reviews Neuroscience, 12(8), 467-477.

Ditye, T., Jacobson, L., Walsh, V., & Lavidor, M. (2012). Modulating behavioral inhibition by tdcs combined with cognitive training. Experimental Brain Research, 219(3), 363-368.

Dulcan, M. (1997). Practice parameters for the assessment and treatment of children, adolescents, and adults with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 36(10), 85S-121S.

Durston, S., Pol, H. E. H., Schnack, H. G., Buitelaar, J. K., Steenhuis, M. P., Minderaa, R. B., … van Engeland, H. (2004). Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings. Journal of the American Academy of Child & Adolescent Psychiatry, 43(3), 332-340.

Fregni, F., Boggio, P. S., Nitsche, M., Bermpohl, F., Antal, A., Feredoes, E.,... Pascual-Leone, A. (2005). Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory. Experimental Brain Research, 166(1), 23-30.

Giglia, G., Brighina, F., Rizzo, S., Puma, A., Indovino, S., Maccora, S.,... Fierro, B. (2014). Anodal transcranial direct current stimulation of the right dorsolateral prefrontal cortex enhances memory-guided responses in a visuospatial working memory task. Functional Neurology, 29(3), 189-193.

Gilbert, D. L., Isaacs, K. M., Augusta, M., MacNeil, L. K., & Mostofsky, S. H. (2011). Motor cortex inhibition:A marker of ADHD behavior and motor development in children. Neurology, 76(7), 615-621.

Gill, J., Shah-Basak, P. P., & Hamilton, R. (2015). It's the thought that counts:Examining the task-dependent effects of transcranial direct current stimulation on executive function. Brain Stimulation, 8(2), 253-259.

Gillick, B. T., Feyma, T., Menk, J., Usset, M., Vaith, A., Wood, T. J.,... Krach, L. E. (2015). Safety and feasibility of transcranial direct current stimulation in pediatric hemiparesis:Randomized controlled preliminary study. Physical Therapy, 95(3), 337-349.

González-Castro, P., Cueli, M., Rodríguez, C., García, T., & Álvarez, L. (2016). Efficacy of neurofeedback versus pharmacological support in subjects with ADHD. Applied Psychophysiology and Biofeedback, 41(1), 17-25.

Hart, H., Radua, J., Nakao, T., Mataix-Cols, D., & Rubia, K. (2013). Meta-analysis of functional magnetic resonance imaging studies of inhibition and attention in attention-deficit/hyperactivity disorder:Exploring task-specific, stimulant medication, and age effects. JAMA Psychiatry, 70(2), 185-198.

Jackson, S. R., Marrocco, R., & Posner, M. I. (1994). Networks of anatomical areas controlling visuospatial attention. Neural Networks, 7(6-7), 925-944.

Jacobson, L., Koslowsky, M., & Lavidor, M. (2012). tDCS polarity effects in motor and cognitive domains:A meta-analytical review. Experimental Brain Research, 216(1), 1-10.

Jeon, S. Y., & Han, S. J. (2012). Improvement of the working memory and naming by transcranial direct current stimulation. Annals of Rehabilitation Medicine, 36(5), 585-595.

Kim, J.-H., Kim, D.-W., Chang, W. H., Kim, Y.-H., Kim, K., & Im, C.-H. (2014). Inconsistent outcomes of transcranial direct current stimulation may originate from anatomical differences among individuals:Electric field simulation using individual MRI data. Neuroscience Letters, 564, 6-10.

Krishnan, C., Santos, L., Peterson, M. D., & Ehinger, M. (2015). Safety of noninvasive brain stimulation in children and adolescents. Brain Stimulation, 8(1), 76-87.

Kuo, M.-F., Paulus, W., & Nitsche, M. A. (2014). Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases. NeuroImage, 85, 948-960.

Leffa, D. T., de Souza, A., Scarabelot, V. L., Medeiros, L. F., de Oliveira, C., Grevet, E. H.,... Torres, I. L. S. (2016). Transcranial direct current stimulation improves short-term memory in an animal model of attention-deficit/hyperactivity disorder. European Neuropsychopharmacology, 26(2), 368-377.

Liang, S. F., Hsieh, T.-H., Chen, P.-T., Wu, M.-L., Kung, C.-C., Lin, C.-Y., & Shaw, F.-Z. (2012). Differentiation between resting-state fMRI data from ADHD and normal subjects:Based on functional connectivity and machine learning. In 2012 International Conference on Fuzzy Theory and It's Applications (iFUZZY) (pp. 294-298). Taichung, Taiwan:IEEE.

Mattai, A., Miller, R., Weisinger, B., Greenstein, D., Bakalar, J., Tossell, J.,... Gogtay, N. (2011). Tolerability of transcranial direct current stimulation in childhood-onset schizophrenia. Brain Stimulation, 4(4), 275-280.

Moliadze, V., Andreas, S., Lyzhko, E., Schmanke, T., Gurashvili, T., Freitag, C. M., & Siniatchkin, M. (2015a). Ten minutes of 1mA transcranial direct current stimulation was well tolerated by children and adolescents:Self-reports and resting state EEG analysis. Brain Research Bulletin, 119, 25-33.

Moliadze, V., Schmanke, T., Andreas, S., Lyzhko, E., Freitag, C. M., & Siniatchkin, M. (2015b). Stimulation intensities of transcranial direct current stimulation have to be adjusted in children and adolescents. Clinical Neurophysiology, 126(7), 1392-1399.

Munz, M. T., Prehn-Kristensen, A., Thielking, F., Mölle, M., Göder, R., & Baving, L. (2015). Slow oscillating transcranial direct current stimulation during non-rapid eye movement sleep improves behavioral inhibition in attention-deficit/hyperactivity disorder. Frontiers in Cellular Neuroscience, 9, 307.

Nitsche, M. A., Boggio, P. S., Fregni, F., & Pascual-Leone, A. (2009). Treatment of depression with transcranial direct current stimulation (tDCS):A review. Experimental Neurology, 219(1), 14-19.

Nitsche, M. A., Fricke, K., Henschke, U., Schlitterlau, A., Liebetanz, D., Lang, N.,... Paulus, W. (2003). Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans. The Journal of Physiology, 553(1), 293-301.

Oliveira, J. F., Zanão, T. A., Valiengo, L., Lotufo, P. A., Benseñor, I. M., Fregni, F., & Brunoni, A. R. (2013). Acute working memory improvement after tDCS in antidepressant-free patients with major depressive disorder. Neuroscience Letters, 537, 60-64.

Peña-Gómez, C., Sala-Lonch, R., Junqué, C., Clemente, I. C., Vidal, D., Bargalló, N.,... Bartrés-Faz, D. (2012). Modulation of large-scale brain networks by transcranial direct current stimulation evidenced by resting-state functional MRI. Brain Stimulation, 5(3), 252-263.

Poreisz, C., Boros, K., Antal, A., & Paulus, W. (2007). Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients. Brain Research Bulletin, 72(4-6), 208-214.

Prehn-Kristensen, A., Munz, M., Göder, R., Wilhelm, I., Korr, K., Vahl, W.,... Baving, L. (2014). Transcranial oscillatory direct current stimulation during sleep improves declarative memory consolidation in children with attention-deficit/hyperactivity disorder to a level comparable to healthy controls. Brain Stimulation, 7(6), 793-799.

Schulz, K. P., Newcorn, J. H., Fan, J., Tang, C. Y., & Halperin, J. M. (2005). Brain activation gradients in ventrolateral prefrontal cortex related to persistence of ADHD in adolescent boys. Journal of the American Academy of Child & Adolescent Psychiatry, 44(1), 47-54.

Shi, J., Wang, Y., Ceschin, R., An, X., Lao, Y., Vanderbilt, D.,... Leporé, N. (2013). A multivariate surface-based analysis of the putamen in premature newborns:Regional differences within the ventral striatum. PLoS One, 8(7), e66736.

Silk, T. J., Vilgis, V., Adamson, C., Chen, J., Smit, L., Vance, A., & Bellgrove, M. A. (2016). Abnormal asymmetry in frontostriatal white matter in children with attention deficit hyperactivity disorder. Brain Imaging and Behavior, 10(4), 1080-1089.

Smith, R. C., Boules, S., Mattiuz, S., Youssef, M., Tobe, R. H., Sershen, H.,... Davis, J. M. (2015). Effects of transcranial direct current stimulation (tDCS) on cognition, symptoms, and smoking in schizophrenia:A randomized controlled study. Schizophrenia Research, 168(1-2), 260-266.

Snyder, S., Quintana, H., Sexson, S. P., Knott, P., Haque, A. F. M., & Reynolds, D. A. (2008). Blinded, multi-center validation of EEG and rating scales in identifying ADHD within a clinical sample. Psychiatry Research, 159(3), 346-358.

Soff, C., Sotnikova, A., Christiansen, H., Becker, K., & Siniatchkin, M. (2017). Transcranial direct current stimulation improves clinical symptoms in adolescents with attention deficit hyperactivity disorder. Journal of Neural Transmission, 124(1), 133-144.

Soltaninejad, Z., Nejati, V., & Ekhtiari, H. (2015). Effect of anodal and cathodal transcranial direct current stimulation on DLPFC on modulation of inhibitory control in ADHD. Journal of Attention Disorders, 101(4), 291-302.

Sonuga-Barke, E. J. S. (2005). Causal models of attention-deficit/hyperactivity disorder:From common simple deficits to multiple developmental pathways. Biological Psychiatry, 57(11), 1231-1238.

Sotnikova, A., Soff, C., Tagliazucchi, E., Becker, K., & Siniatchkin, M. (2017). Transcranial direct current stimulation modulates neuronal networks in attention deficit hyperactivity disorder. Brain Topography, 30(5), 656-672.

Spencer, T. J., Brown, A., Seidman, L. J., Valera, E. M., Makris, N., Lomedico, A.,... Biederman, J. (2013). Effect of psychostimulants on brain structure and function in ADHD:A qualitative literature review of MRI-based neuroimaging studies. The Journal of Clinical Psychiatry, 74(9), 902-917.

Toone, B. (2004). Attention deficit hyperactivity disorder in adulthood. Journal of Neurology Neurosurgery & Psychiatry, 75(4), 523-525.

Truong, D. Q., Magerowski, G., Blackburn, G. L., Bikson, M., & Alonso-Alonso, M. (2013). Computational modeling of transcranial direct current stimulation (tDCS) in obesity:Impact of head fat and dose guidelines. NeuroImage:Clinical, 2, 759-766.

Valera, E. M., Faraone, S. V., Murray, K. E., & Seidman, L. J. (2007). Meta-analysis of structural imaging findings in attention-deficit/hyperactivity disorder. Biological Psychiatry, 61(12), 1361-1369.

Wankerl, B., Hauser, J., Makulska-Gertruda, E., Reißmann, A., Sontag, T. A., Tucha, O., & Lange, K. W. (2014). Neurobiology of attention deficit hyperactivity disorder. Fortschritte der Neurologie-Psychiatrie, 82(1), 9-29.

Wei, H., Zou, H., Sheikh, A. M., Malik, M., Dobkin, C., Brown, W. T., & Li, X. (2011). IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation. Journal of Neuroinflammation, 8, 52.

Wu, Y.-J., Tseng, P., Chang, C.-F., Pai, M.-C., Hsu, K.-S., Lin, C.-C., & Juan, C.-H. (2014). Modulating the interference effect on spatial working memory by applying transcranial direct current stimulation over the right dorsolateral prefrontal cortex. Brain and Cognition, 91, 87-94.

Xia, S., Li, X., Kimball, A. E., Kelly, M. S., Lesser, I., & Branch, C. (2012). Thalamic shape and connectivity abnormalities in children with attention-deficit/hyperactivity disorder. Psychiatry Research:Neuroimaging, 204(2-3), 161-167.

Yang, H., Wu, Q.-Z., Guo, L.-T., Li, Q.-Q., Long, X.-Y., Huang, X-Q.,... Gong, Q.-Y. (2011). Abnormal spontaneous brain activity in medication-naive ADHD children:A resting state fMRI study. Neuroscience Letters, 502(2), 89-93.

Zaehle, T., Sandmann, P., Thorne, J. D., Jäncke, L., & Herrmann, C. S. (2011). Transcranial direct current stimulation of the prefrontal cortex modulates working memory performance:Combined behavioural and electrophysiological evidence. BMC Neuroscience, 12, 2.

Zhu, Y., Yang, D., Ji, W., Huang, T., Xue, L., Jiang, X.,... Wang, F. (2016). The relationship between neurocircuitry dysfunctions and attention deficit hyperactivity disorder:A review. Biomed Research International, 2016, 3821579.