DOI: 10.3724/SP.J.1042.2018.01450

Advances in Psychological Science (心理科学进展) 2018/26:8 PP.1450-1464

The influence factors and neural mechanisms of inhibitory control in autism spectrum disorders

Autism spectrum disorder (ASD) is a neurodevelopmental disorder in childhood. The repetitive behavior of people with ASD is closely related to the development of inhibitory control. The studies which used of Go/No-go, Flanker and Stroop tasks found that the inhibitory control of people with ASD was mainly manifested as a deficit in response inhibition and interference inhibition. Task status, subjects age and sampling were the main factors that affected inhibitory control of people with ASD. Previous studies have shown that inhibitory control correlated with brain regions including:prefrontal cortex, anterior cingulate cortex and basal ganglia. The genes related to inhibitory control including:glutamate, gamma aminobutyric acid and 5-serotonin. The future study should start with the research of brain mechanism, taking into account the influence of task status and individual characteristics on the research results, and put forth effort to the development of more effective intervention model.

Key words:autism,inhibitory control,network connection,brain mechanism

ReleaseDate:2018-08-27 09:44:19

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