DOI: 10.3724/SP.J.1095.2013.20574

Chinese Journal of Applied Chemistry (应用化学) 2013/30:12 PP.1494-1496

Synthesis of 3,6-diarylpyrazolo[1,5-a]pyrimidines

Twelve new 7-substituted-3,6-diarylpyrazolo[1,5-a]pyrimidines were synthesized by the aminizations of the derivatives of 5,7-dichloro-3-(2,4-dichlorophenyl)-2-methyl-6-phenylpyrazolo [1,5-a] pyrimidine. These derivatives were prepared by the reaction of 3-(2,4-dichlorophenyl)-2-methyl-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diol and phosphorus oxychloride. The products were characterized by IR, 1H NMR, elemental analysis and single crystal X-ray diffraction analysis.

Key words:pyrazolo[1,5-a]pyrimidine,chlorination,aminization,crystal structure

ReleaseDate:2015-06-08 13:48:07

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