DOI: 10.3724/SP.J.1145.2010.00261

Chinese Journal of Appplied Environmental Biology (应用与环境生物学报) 2010/16:2 PP.261-263

Secondary Metabolites with Anti-Staphylococcus aureus Activity from Streptomyces hygroscopicus*

By monitoring and studying the antibacterial activity of Streptomyces hygroscopicus 1.358 against Staphylococcus aureus, three compounds (1~3) were isolated from the ethyl acetate extract of the broth culture of S. hygroscopicus, and They were determined as RK 955A (1), nigericin (2) and elaiophylin (3) on the basis of spectroscopic data. Compounds 1~3 showed significant antibacterial activities against S. aureus. Fig 1, Tab 1, Ref 18

Key words:Staphylococcus aureus,Streptomyces hygroscopicus,nigericin,elaiophylin,secondary metabolite,antibacterial activity

ReleaseDate:2014-07-21 15:22:46

Funds:Supported by the Knowledge Innovation Program of the Chinese Academy of Sciences

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