doi:

DOI: 10.3724/SP.J.1123.2019.06015

Chinese Journal of Chromatography (色谱) 2019/37:12 PP.1368-1372

Determination of two non-phthalates plasticizers in edible oil by gas chromatography-tandem mass spectrometry


Abstract:
A gas chromatography-tandem mass spectrometry (GC-MS/MS) method was developed for the simultaneous determination of di (2-ethylhexyl) terephthalate and tris (2-ethylhexyl) trimellitate in edible oils. The plasticizers in the samples were extracted with acetonitrile. The extract was purified by freezing at -20 ℃, and determined by GC-MS/MS in selective reaction monitoring mode. For the two compounds, the limit of detection and limit of quantification were 0.03 mg/kg and 0.1 mg/kg, respectively, and the linear range was 0.1-10 mg/kg. The recoveries of the two compounds ranged from 81.04% to 108.31% at three spiked levels (0.1, 0.3, and 1.0 mg/kg), and the relative standard deviation ranged from 0.70% to 9.91%. The method is simple, accurate, and suitable for the determination of di (2-ethylhexyl) terephthalate and tris (2-ethylhexyl) trimellitate in edible oils.

Key words:gas chromatography-tandem mass spectrometry (GC-MS/MS),di-2-ethylhexyl terephthalate,tris (2-ethylhexyl) trimellitate,edible oil

ReleaseDate:2019-12-02 10:05:20



[1] Xu W Y, Yi S F, Liao Y Z, et al. Chinese Journal of Health Laboratory Technology, 2016, 26(20):2894 徐文泱, 易守福, 廖燕芝, 等. 中国卫生检验杂志, 2016, 26(20):2894

[2] Liu S J, Fang C G, Li Q, et al. Chinese Journal of Health Laboratory Technology, 2012, 22(3):598 刘思洁, 方赤光, 李青, 等. 中国卫生检验杂志, 2012, 22(3):598

[3] Zhou J, Liu M, Zeng X L, et al. Progress in Modern Biomedicine, 2015, 15(28):5558 周杰, 刘淼, 曾晓龙, 等. 现代生物医学进展, 2015, 15(28):5558

[4] Tian L, Hu J W, Wang W, et al. Modern Preventive Medicine, 2018, 45(21):3891 田丽, 胡佳薇, 王玮, 等. 现代预防医学, 2018, 45(21):3891

[5] Rao X X, Wang J C, Zhou Z F. Acta Scientiae Circumstantiae, 2017, 37(4):1531 饶潇潇, 王建超, 周震峰. 环境科学学报, 2017, 37(4):1531

[6] Liao Y Z, Chen G, Liu P. China Oils and Fats, 2018, 43(6):90 廖燕芝, 陈耕, 刘璞. 中国油脂, 2018, 43(6):90

[7] Xu T Y, Hu J B, Gao H S, et al. Chinese Journal of Clinical Laboratory Science, 2013, 31(1):51 徐廷云, 胡嘉波, 高华生, 等. 临床检验杂志, 2013, 31(1):51

[8] Lin L, Huang D M, Huang M L, et al. Journal of Guangxi Medical University, 2018, 35(6):869 林琳, 黄大敏, 黄明立, 等. 广西医科大学学报, 2018, 35(6):869

[9] Yang Z P, Jin Q, Zhou B, et al. Journal of Environmental and Occupational Medicine, 2014, 31(5):331 杨章萍, 金铨, 周标, 等. 环境与职业医学, 2014, 31(5):331

[10] Deyo J A. Food Chem Toxicol, 2008, 46(3):990

[11] Faber W D, Deyo J A, Stump D G, et al. Birth Defects Res B, 2007, 80(5):396

[12] Chen X H, Ma L, Hu Y X, et al. Environ Toxicol Phar, 2016, 41:62

[13] Ji Y B, Xu G M, Luo H, et al. Plastics, 2012, 41(2):41 吉玉碧, 徐国敏, 罗恒, 等. 塑料, 2012, 41(2):41

[14] Zhang L, Zheng J, Xu P H, et al. Chinese Journal of Pharmaceutical Analysis, 2017, 37(11):2106 张莉, 郑建, 徐萍华, 等. 药物分析杂志, 2017, 37(11):2106

[15] Christine H, Günther B, Thomas G, et al. Arch Toxicol, 2018, 92(9):2793

[16] Ito R, Miura N, Iguchi H, et al. Int J Pharm, 2008, 360(1/2):91

[17] Guo M, Qiao H Q, Mao L S. Chinese Journal of Hospital Pharmacy, 2015, 35(3):227 郭敏, 乔红群, 毛黎顺. 中国医院药学杂志, 2015, 35(3):227

[18] Fan J C, Jin Q, Zhang L, et al. J AOAC Int, 2014, 97(4):1151

[19] Wei J F, Jiang L, Lou C Y, et al. Chinese Journal of Chromatography, 2018, 36(7):678 韦俊芳, 姜磊, 楼超艳, 等. 色谱, 2018, 36(7):678

[20] Zhang L, Shang C X, Sun C. Chinese Journal of Chromatography, 2014, 32(6):653 张莉, 尚楚翔, 孙成. 色谱, 2014, 32(6):653

[21] Chen R, Shu T, Ma M F, et al. Chemistry, 2014, 77(5):477 陈睿, 束彤, 马明芳, 等. 化学通报, 2014, 77(5):477

[22] Zhang M M, Liu Y L, Ma Y X, et al. China Oils and Fats, 2015, 40(2):56 张明明, 刘玉兰, 马宇翔, 等. 中国油脂, 2015, 40(2):56

[23] Zhang F, Li Z H, Zhang Y, et al. Chinese Journal of Chromatography, 2014, 32(7):735 张帆, 李忠海, 张莹, 等. 色谱, 2014, 32(7):735

[24] Li X, Wu W J, Liu J, et al. The Food Industry, 2018, 39(2):301 李旭, 吴维吉, 刘佳, 等. 食品工业, 2018, 39(2):301

[25] Jin X Z, Gao H Y, Wang Z, et al. Chinese Journal of Chromatography, 2018, 36(2):173 金香子, 高汉勇, 王钊, 等. 色谱, 2018, 36(2):173