Journal of Inorganic Materials (无机材料学报) 2014/29:7 PP.769-775
As the second essential trace element in human body, copper plays vital roles in metabolism and antimicrobial. Therefore, synthesis of copper-substituted hydroxyapatite (Cu-HA) is expected to create bioceramics with improved biological and antimicrobial properties. In this study, Cu-HA was prepared by hydrothermal reactions using Ca(NO3)2·4H2O, Cu(NO3)2·3H2O and Na2HPO4·12H2O. Products were characterized by scanning electron microscope, transmission electron microscope, X-ray diffraction, Fourier transform infrared spectroscope and atomic absorption spectrometry. Results show that copper is incorporated into the HA crystals. Correspondingly, the products retain a HA structure but their morphologies transform from ribbons to flower-like microspheres. Moreover, when Cu/(Cu+Ca) (molar ratio) of the reaction solution is greater than 0.05, the thermal stability of the HA product is decreased.
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