DOI: 10.3724/SP.J.1249.2017.05451

Journal of Shenzhen University Science and Engineering (深圳大学学报理工版) 2017/34:5 PP.451-456

Preparation and characterization of hydroxyapatite-chitosan composite coatings using a spin-coating technique

Based on a chemical precipitation method, the hydroxyapatite powders were prepared using Na2HPO4 and Ca(NO3)2·4H2O as raw materials. The powders were dispersed into chitosan-acetic acid solution with the aid of continuous ultrasonic agitation to prepare hydroxyapatite-chitosan (HA-CS) suspension via solution blending and magnetic stirring. Hydroxyapatite-chitosan composite coatings were fabricated on 304-type stainless steel substrates by a spin-coating technique, then dried at 25℃ and 37℃ for 12 h, respectively. The two synthesized samples were characterized and tested by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and electronic tensile machine. The results indicate the tensile strength of HA-CS composites reaches up to (69.04±1.21) MPa, and the coatings display good crystallinity, good adhesion, high purity and little decomposition. In addition, by means of spin-coating technique, HA could be evenly dispersed in CS and there are no aggregated or free HA particles in the coatings. The HA-CS composite coatings show better performance when drying at 37℃ than at 25℃, which is more conducive to combine interaction between HA and CS.

Key words:biomaterials science,hydroxyapatite,chitosan,composite coatings,spin-coating technique,mechanical property

ReleaseDate:2017-10-20 02:07:29

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