doi:

DOI: 10.3724/SP.J.1206.2012.00623

Progress in Biochemistry and Biophysics (生物化学与生物物理进展) 2013/40:12 PP.1177-1185

Progress on The Autophagy in Vessel Function and Related Diseases


Abstract:
Autophagy which is a process that damaged organelles and cellular proteins are degraded by lysosomes plays a critical role in cellular homeostasis. Previous studies have demonstrated that autophagy influenced the vascular function, even involved in the pathophysiology of vascular diseases. In this review we focus on the effect of autophagy on the vascular function and vascular diseases such as atherosclerosis, abdominal aortic aneurysm,pulmonary hypertension and diabetes mellitus. Moreover, we try to provide a new way of vascular diseases treatment from the point of autophagy.

Key words:autophagy,vascular function,vascular diseases,drug

ReleaseDate:2015-04-18 09:14:48



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