DOI: 10.3724/SP.J.1145.2010.00289

Chinese Journal of Appplied Environmental Biology (应用与环境生物学报) 2010/16:2 PP.289-293

Progress in Research of Insect orthodenticle Gene*

The embryogenesis of insect is controlled by a series of genes, which are turned on or off according to a precise time and spatial sequence to regulate the growth and differentiation of embryonic cells. Among these genes, orthodenticle (otd) encodes a regulatory transcription factor and plays a key role in embryogenesis of insect. In some insects without bicoid gene, otd partially substitutes for bicoid function and establishes the polarity of anterior-posterior axis in early embryogenesis. Furthermore, otd gene also involves in the process of cephalic segmentation, and developments of eyes and nervous system. At present, there are some insects about the otd gene function study, such as Drosophila melanogaster, Tribolium castaneum and Nasonia vitripennis, and it is very difference that the otd gene sequences, expression patterns and functions in the insects. In this paper, the otd gene is reviewed, including its structure, function and evolution throughout insects in order to provide an information frame for promoting the research of this gene. Fig 1, Ref 62

Key words:orthodenticle gene,insect,embryonic development,patterning formation,cephalic segmentation

ReleaseDate:2014-07-21 15:22:50

Funds:Supported by the National Natural Science Foundation of China (No. 30700435) and the Natural Science Foundation of Chongqing, China (Nos. CSTC2008BA5030, CSTC2009BB1387)

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